Natreon’s Capros® Ingredient Significantly Improved Endothelial Function, Oxidative Stress, Immune Response, and Lipid Profile in Metabolic Syndrome
Dr. Sanni Raju, CEO & Chairman or Bruce Brown, President
2-D Janine Place
New Brunswick, NJ 08901
NEW BRUNSWICK, NJ, JUNE 20, 2019– Natreon, a leader in natural ingredient research and innovation, announces its latest results in the recently published clinical study on Capros, its branded Phyllanthgus emblica fruit extract. During this 12-week trial, Capros showed significant improvement in endothelial function, oxidative stress, immune response and lipid profile. This marks the 12th clinical trial published by Natreon for its innovative heart healthy amla extract.
Out of the 65 screened subjects, 59 eligible subjects were randomized and completed the study. The study consisted of two different dosages of Phyllanthus emblica extract – 250 mg and 500 mg twice daily. Both dosages showed significant improvement in endothelial function (vascular health), oxidative stress biomarkers-Nitric oxide (+ 41.89%, + 50.7%), Glutathione (+ 24.31%, + 53.22%), Malondialdehyde (- 21.02%, – 31.44%), and systemic inflammation biomarker, hsCRP (- 39.68%, – 53.77%) at 12 weeks with 250 mg and 500 mg twice daily dosage respectively, compared to baseline and placebo. Results also showed a significant mean percent change at 12 weeks with total cholesterol (- 7.71%, – 11.11%), HDL-C (+ 7.33% + 22.16%), LDL-C (- 11.39%, – 21.8%) and Triglycerides (- 9.81%, – 19.22%) respectively with 250 mg and 500 mg twice daily. The 500 mg twice daily dose was significantly more efficacious than the 250 mg twice daily dose and placebo. Thus, this product may be used as an adjunct to conventional therapy (lifestyle modification and pharmacological intervention) in the management of metabolic syndrome.
Reference: BMC Complement Altern Med. 2019 May 6;19(1):97. doi: 10.1186/s12906-019-2509-5
Dr. Sanni Raju, CEO of Natreon, stated that “Capros has all the attributes of being an excellent heart health product and has been consistently proven to be so in multiple clinical studies. This latest trial once again has shown the ability of Capros to improve vascular health, reduce oxidative stress, improve the lipid profile, especially by reducing the LDL and triglycerides. It also has shown to enhance immune response by reducing hsCRP and
improve blood flow.” Dr. Raju also says that “Capros is a totally natural and vegan edible fruit aqueous extract and when combined with its recently issued US Patent (8,962,576) on composition and methods for improving endothelial function and cardiovascular health, Capros’ solubility, stability and taste, make it an ideal heart health product for capsule, powder and beverage formations.”
Capros is a heart healthy superfruit extract derived from the edible fruits of amla, Phyllanthus emblica. Capros is a multi-patented adaptogen standardized to low molecular weight hydrolysable tannins (emblicanin A, emblicanin B). It is an antioxidant-rich superfruit with an ORACFN value of 47,000 μmoles TE/g that supports cardiovascular health through its numerous benefits. Capros is backed by 12 clinical studies proven to help support endothelial function and protect the body against oxidative stress. It also helps in supporting a healthy immune response and healthy blood flow. Capros uses an aqueous extraction process and is organic, vegan, gluten free, GRAS affirmed, and Non-GMO Project Verified.
Natreon is a leader in nutritional ingredient innovation, quality and research. Trusted by manufacturers for over 20 years, Natreon’s patented ingredients are derived from nature and founded on evidence-based Ayurveda. Committed to quality, its extracts are purified and standardized using proprietary process technology and controls that result in optimal levels of bioactive constituents. Natreon’s ingredients have been tested in multiple clinical (52 as of this date) and are GRAS-affirmed to ensure efficacy, safety and authenticity. Natreon brings storied knowledge and expertise in botanical cultivation and extraction, and its ingredients are sustainably sourced through an integrated supply chain to ensure quality and potency. Natreon has its global headquarters in New Jersey and a state-of-the-art R&D facility in Kolkata, India.